Tests with Mepacrine Hydrochloride, B.P. against Plasmodium Relictum
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چکیده
further reference. The report deals with the three remaining birds. Methods.?The infections were induced by intramuscular inoculation of parasitised blood from an artificially infected sparrow. The birds were treated after the appearance of parasites in the peripheral blood, but before the acute stage had developed. If treatment is left to a later stage it may be difficult to say whether a reduction in the number of parasites is due to the action of a drug or to the natural recovery which is usually evident in infections with this strain of P. relictum. The dosage employed was 5 mg. per 20 g. of body-weight of bird; this dose was lound by Tate and Vincent (1934) to be the
منابع مشابه
The Effect of Indian-Made Mepacrine Hydrochloride on Plasmodium Knowlesi *Prepared by Bengal Chemical and Pharmaceutical Works Ltd., Calcutta.
The satisfactory results obtained in the treatment of bird malaria (P. relictum) with mepacrine hydrochloride (Das Gupta and Siddons, 1943) encouraged us to try it in P. knowlesi infection in the monkey, Silenus rhesus. It is well known that, in this monkey^ this parasite produces the most intense infection which, if unchecked, usually terminates fatally. Therefore, infected monkeys are very su...
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